Research use only PNC-27
Longevity & Cellular Research Peptides 4.6

PNC-27

A 32-residue chimeric peptide joining residues 12 to 26 of the p53 tumour-suppressor protein to a membrane-residency domain derived from penetratin.


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Documented batch Each size ships with the certificate issued for its own fill. This is what is on file for the size selected above.
99.90% Purity by HPLC
Batch
ACE-1756914
Identity
Confirmed by mass spectrometry
On file
Purity & Identity
Technical specification

What is on file, and how it is handled

Every figure below is transcribed from the paperwork for this compound.

What is PNC-27?

The p53 portion carries the HDM-2 binding domain; the penetratin portion is what carries it into the membrane. The published interest in the molecule is that HDM-2 is expressed in the plasma membrane of some cell lines and not others, which is the selectivity the chimera was designed around. Studied in membrane-binding and cell-lysis models.

Material

Compound
PNC-27
Form
Lyophilised powder

Verification

Identity
Confirmed by mass spectrometry
Purity
See certificate
Batch
See certificate
Documentation
Per-batch certificate of analysis

Handling

Storage
Store at −20 °C, protected from light
Intended use
In-vitro laboratory research only

ReviewsWhat researchers say